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Steroid drugs, such as prednisone, work by lowering the activity of the immune system. The immune system is your body’s defense system. Steroids work by slowing your body’s response to disease or injury. Prednisone can help lower certain immune-related symptoms, including inflammation and swelling. Dexamethasone is used to reduce inflammation and suppress the immune system in cases where it’s not functioning properly. They are commonly used to treat mild inflammatory conditions and/or to suppress the inflammation associated with an allergic response. When administered in high doses, they act as immunosuppressant drugs meaning they suppress or prevent an immune response. They work by decreasing inflammation and reducing the activity of the immune system. Steroid injections are one of the most effective ways to ease pain and improve your ability to move, but they. When we supplement with anabolic androgenic steroids our natural production is suppressed; the total duration of the cycle, the compounds used and the total dose will affect this to a degree, some steroids suppress more than others but suppression will exist regardless to some level